PharmaLIBS™250

PharmaLIBS™250 is an innovative, patented, laser-based analytical instrument designed for rapid,
reliable testing of solid and oral dosage pharmaceuticals.

Full safety interlocks protection. Class I Laser System (No safety eyewear necessary)
Internal ventilation system specially designed for the Pharmaceutical Industry.
Wheeled for mobility

 

 

 

 

Advantages

The PharmaLIBS™ 250 will help you increase your productivity:

No Sample preparation
Plug and play (no hidden installation costs)
Instantaneous qualitative results
Up to 100 individual tablets site determinations in 1 minute
3D special resolution
Identify absolute location of dosage form components
Unique ability to locate segregated components in depth throughout the tablet
Applicable to coated tablets and/or non coated tablets/ granules/ capsules/ powder
Process monitoring
Multi-element measurements
Detection of metallic and other impurities
Unambiguous spectral signature
Simplicity of calibration procedure
No consumable
No reagent
No hazardous material required
Low long-term cost
Adapt easily to any sample shape and size
Mobile



Instrumental Specifications:

Integrated High Power Computer
Dimensions: 135 cm x 60 cm x 99 cm (53" x 24" x 39")
Weight: 130 kg (273 lbs)
Wheeled for mobility
Fully safety interlocks protection
Larger laser-safe viewing port
HEPA filtration system



Sample Tray

• Capacity up to 26 sample

• Laser sampling position are fully software selectable

• Removable sample holders for customization to sample size and shape

• Reusable sample holders



CDRH Classification:

Class 1 Laser System (No safety eyewear necessary)



Laser:

Pulsed Nd-YAG laser operated at fundamental wavelength of 1064 nm
Pulse duration: 3-5 ns
Pulse energy: computer controlled, up to 190 mJ per pulse
Repetition rate: computer controlled, up to 10 Hz
Spot size: ~ 200 μm



Spectrograph:

Imaging Czerny-Turner configuration
Triple selectable grating (better resolution)
Spectral resolution: 0.1 nm
Grating and Wavelength selection under full computer control.



CCD Detector:

Interline readout scientific grade CCD
Thermoelectrically cooled
Electronic grating
Exposure window: 100 nm and up
Spectral sensitivity rage 300-1000 nm



System Software

PharmaLIBS™ 250 software
Fully automated data acquisition and results processing 'Methods' based
Real time display of acquired spectra and processed results
Graphical and tabular output data
Data export to text and Microsoft Excel format
Graphical export to BMP, WMF and JPG formats
Fully 21 CFR Part 11 Compliant Software

Coating Thickness Study by Dr. Fernado J. Muzzio

Three techniques combined to better understand the Tablet Coating Thickness Uniformity problematic.
Coating Thickness Study by Dr. Fernado J. Muzzio

Financing from Canadian Government available

Export Development Canada can provide financing directly to our foreign customers for an export sale of capital goods such as the PharmaLIBS 250.
Financing from Canadian Government available

VALIDATED METHOD

Pharma Laser is proud to announce a validated method for pharmaceutical applications in collaboration with the FDA. The first LIBS validated method for quantification in the world...
VALIDATED METHOD

FACSS

October 18 - 22, 2009 The 36th FACSS will be held in Louisville, KY Pharmaceutical Analysis: More than just chromatography Stéphane Mallette, VP Pharma Laser
FACSS

AAPS

November 8 - 12, 2009 Los-Angeles Convention Center, Los-Angeles CA Booth 729
AAPS